摘要目的 客观评估和比较不同年龄段成年人眼的综合光学质量.方法 横断面研究.收集20～ 70岁最佳矫正视力≥4.9的432例(432只眼)对象进行研究,其中双眼视力相同的随机选取一眼,双眼视力不同的选择视力较好的眼.以10岁为间隔分为5个年龄段组.采用光学质量分析系统(OQASⅡ)客观测量人眼的综合光学质量,参数包括调制传递函数(MTF)截止频率、Strehl比、客观散射指数(OSI)、3个OQAS值(OV100％、OV20％、OV9％).采用单因素方差分析比较各组之间光学质量参数的差异.结果 20～29岁、30～ 39岁、40～49岁、50～59岁、60～ 69岁组的MTF截止频率分别为(43.91±7.43)、(40.93±9.92)、(37.16±9.04)、(36.69±7.87)、(28.52±8.31)周/度;Strehl比分别为0.26±0.06、0.24±0.06、0.20±0.05、0.20±0.04、0.16±0.04;OV100％分别为1.47±0.24、1.36±0.33、1.24±0.30、1.22±0.26、0.96±0.28;OV20％分别为1.51±0.33、1.40±0.38、1.22±0.36、1.20±0.28、0.91±0.32;0V9％分别为1.14±0.26、1.41±0.40、1.20±0.37、1.18±0.28、0.89±0.28;OSI分别为0.42±0.24、0.53±0.32、0.54±0.34、0.54±0.26、1.06±0.56.MTF截止频率、Strehl比、OV100％、OV20％除了40～49岁组与50～59岁组差异无统计学意义之外(P＞0.05),其余差异有统计学意义(P＜0.05).Ov9％除了20～ 29岁组、40～ 49岁组、50～59岁组之间差异无统计学意义之外(P＞0.19),其余比较的差异有统计学意义(P＜0.05).OSI除了30～ 39岁组、40 ～49岁组、50 ～59岁组三者之间差异无统计学意义之外(P＞0.70),其余比较的差异有统计学意义(P≤0.04).结论眼综合光学质量除了在中年人群存在平台期之外,年轻组优于年长组.

abstractsObjective To objectively assess and compare comprehensive optical quality among adults at different ages.Methods In this cross-sectional study, there were 432 subjects (432 eyes) aged from 20 to 70 years with best corrected visual acuity (BCVA) better than 4.9.If both eyes of a subject had equal BCVA, one eye was selected randomly.Otherwise, the eye with better BCVA was chosen.The patients were divided into 5 groups at an age interval of 10 years.The optical quality analysis system Ⅱ (OQAS 11) was used to measure the following optical quality parameters: the modulation transfer function cutoff frequency (MTFcutoff), the Strehl ratio, three OQAS values (OV100％, OV20％, and OV9％), and the objective scatter index (OSI).Each optical quality parameter was compared among different groups by One-way ANOVA.Results In the groups of 20-29 years, 30-39 years, 40-49 years, 50-59 years, and 60-69 years, the MTFcutoffwas (43.91±7.43), (40.93±9.92), (37.16±9.04), (36.69±7.87), and (28.52±8.31) cpd, respectively;the Strehl ratio was 0.26±0.06, 0.24±0.06, 0.20±0.05, 0.20±0.04, and 0.16±0.04, respectively;the OV100％ was 1.47±0.24, 1.36±0.33, 1.24±0.30, 1.22±0.26, and 0.96±0.28, respectively;the OV20％ was 1.51±0.33, 1.40±0.38, 1.22±0.36, 1.20±0.28, and 0.91 ±0.32, respectively;the OV9％ was 1.14±0.26, 1.41 ±0.40, 1.20± 0.37, 1.18±0.28, and 0.89±0.28, respectively;the OSI was 0.42±0.24, 0.53±0.32, 0.54±0.34, 0.54±0.26, and 1.06±0.56, respectively.There were significant differences in the mean values of MTFcutoff, Strehl ratio, OV100％, and OV20％ among groups (P＜0.05), except for the groups of 40-49 years and 50-59 years (P＞ 0.05).The OV9％ was significantly different among groups (P＜0.05), except for the groups of 20-29 years, 40-49 years, and 50-59 years (P＞0.19).The OSI was also significantly different among groups (P＜0.05), except for the groups of 30-39 years, 40-49 years, and 50-59 years (P＞0.70).Conclusion The comprehensive optical quality in the young healthy population is better than the old, except for a plateau in the middle-aged population.