摘要干眼是眼科门诊常见病.随着周围环境和生活方式的改变,该病的发生率逐年升高.目前尚无干眼的诊断金标准,主要依靠结合患者症状、体征进行综合评估.然而干眼症状体征分离现象常给临床诊疗带来压力.近年来的研究发现,干眼感觉神经性疼痛在干眼症状体征分离现象中的作用不可忽视.本文就疼痛的概念、眼表神经的分布与功能、疼痛的发生机制、干眼疼痛的流行病学及镇痛治疗等方面进行简要综述.

abstractsDry eye is one of the most common ocular problems in ophthalmology clinic.With the change of social environment and people's life style,the prevalence of dry eye disease is increasing.Currently,the diagnosis criteria for dry eye is controversial,diagnosis of dry eye mainly rely on the comprehensive assessment of symptoms and the presence of associated ocular surface signs.However,previous studies have shown a poor correlation between dry eye symptoms and objective clinical signs in patients.Recent studies have found that neuropathic pain plays an important role in the occurrence of discordance between symptoms and signs in dry eye disease.The purpose of this paper is to present the conception of pain,the distribution and function of sensory nerves in ocular surface,the prevalence and mechanism of neuropathic pain and analgesic treatment in dry eye disease.