摘要目的 初步分析健康体检人群螃蟹不耐受的阳性率及其相关因素.方法 选择2008年8月至2009年7月来解放军总医院健康体检中心第1次健康体检所有进行螃蟹不耐受检测且数据完整者12 765例进行横断面调查,以问卷方式收集数据,Epidata3.0建库,双人录入,自动排查,应用Logistic模型进行多因素分析.结果 该人群螃蟹不耐受阳性率为24.5％ (3128/12 765),且随年龄增加而升高,不同分级与年龄存在线性相关趋势(P＜0.05),女性(27.5％,1077/3912)显著高于男性(23.2％,2051/8853,P＜0.05).多因素分析显示,螃蟹不耐受与年龄、性别、体质指数和幽门螺杆菌感染显著相关(均P ＜0.05),其中年龄因素,与40岁以下组比较,41 ～50岁组、51 ～60岁组和60岁以上组OR值(95％CI)分别为1.224( 1.095～1.368)、1.616(1.431～1.827)和2.177(1.799 ～2.634)；与男性比较,女性的OR值为1.286(1.174～1.408),幽门螺杆菌感染的OR值为1.303(1.201～1.413)；与正常体重者比较,肥胖者的OR值为1.154(1.026～1.298).结论 该健康体检人群中螃蟹不耐受与年龄、性别、幽门螺杆菌感染和体质指数等因素可能相关,健康干预应针对其特点进行.

abstractsObjective To explore the positive rate of crab intolerance and its related factors in a healthy physical examination population in Beijing,China.Methods A cross-sectional survey was carried out from August 1,2008 to July 30,2009.It recruited a total of 12 765 adults with crab intorlerance at Health Sciences Center,Chinese PLA General Hospital.The epidemiological data were entered into computer by two persons and organized by Epidata3.0.Non-conditional Logistic regression model was used to calculate the values of odd ratio (OR) and 95％ CI.Statistic analysis was performed by SPSS 13.0.Results The incidence rate of crab intolerance was 24.5％ (3128/12 765 ) and increased with age.Grades of crab intolerance were associated with age and gender and there was a linear correlation tendency (P＜0.05).Incidence rate of crab intolerance in females (27.5％,1077/3912)was higher than that of males(23.2％,2051/8853).Multiple regression analysis showed that crab intolerance was correlated with age,gender,body mass index and helicobacter infections(all P＜0.05).In comparison with age group ＜40 years old,the values of OR(95％ CI)of age groups 41 -50,51 -60 and ＞ 60 years old were 1.224( 1.095 - 1.368),1.616( 1.431 - 1.827 ) and 2.177 ( 1.799 - 2.634 ) respectively.In comparison with males,the OR ( 95％ CI) of females was 1.286(1.174 -1.408).The OR(95％CI)of Helicobacter pylori infections was 1.303( 1.201 -1.413).In comparison with normal weighters,the OR(95％ CI)of obese subjects was 1.154 ( 1.026 - 1.298 ).Conclusions Crab intolerance may be correlated with age,gender,Helicobacter pylori infections and body mass index.Health education should be targeted at its characteristics.