摘要目的 建立一组能在磁共振功能成像(fMRI)上分别稳定激活大脑主要汉语功能区的检测方法,使之应用于神经外科术前语言区定位.方法 选用健康志愿者8例,语言区附近病变患者3例,应用西门子3T TrioTim MRI分别进行不同汉语任务下的fMRI扫描.汉语任务包括同义字判断任务、朗读单字任务和听力理解任务.采用SPM8软件进行数据处理和分析后得到脑功能激活图.结果 3种语言任务分别主要激活左侧额中回(BA9区),左侧额下回(Broca区),左侧颞上回(Weericke区).结论 同义字判断任务、朗读单字任务和听力理解任务组成的一套语言任务可以激活中国人主要汉语功能区,可能会成为术前定位语言区的有效方法.

abstractsObjective To design a set of functional magnetic resonance imaging (fMRI) tasks to activate the major Chinese language functional areas.Methods Eight volunteers and 3 patients received fMRI studies with the tasks of semantic judgment,word reading and listening comprehension.Brain activation map of each task was obtained after standard fMRI data processing.Results The fMRI examination with 3 tasks activated middle frontal gyrus (BA 9),Broca area and Wernicke area respectively.Conclusion A set of fMRI examinations,including semantic judgment,word reading and listening comprehension,can activate the major Chinese language functional areas steadily and may be used as a preoperative localizer of language areas.