摘要目的：比较Coopdech 支气管封堵器与双腔支气管导管在儿童单肺通气中的应用。方法选择中山大学附属汕头医院麻醉科2012年1月至2013年6月40例择期单肺通气行胸外科手术的患儿，经医院伦理委员会审核批准，按随机数字表法分为Coopdech支气管封堵器组（ A组，n＝20）和双腔支气管导管组（B组，n＝20），两组患儿分别通过Coopdech 支气管封堵器和双腔支气管导管实现单肺通气。记录两组患儿插管时间、插管成功率、术侧肺萎陷优良率和术后喉痛声嘶发生率，记录两组患儿单肺通气前后动脉二氧化碳分压（PaCO2）、动脉氧分压（PaO2）和气道压（PAW）的变化。结果 A组插管时间明显长于B组[（224±72）比（165±46）s，P＜0.05]，A组插管成功率（100％比85％，P＜0.05）、术侧肺萎陷优良率明显高于B组（95％比75％，P＜0.05），A组术后喉痛声嘶发生率明显低于B组（10％比35％，P＜0.05）；单肺通气30 min后A组PaO2明显高于B组[（206±58）比（148±63） mmHg，1 mmHg＝0.133 kPa，P＜0.05]，PaCO2和PAW明显低于B组[（36±4）比（45±7） mmHg；（21.6±3.2）比（29.3±5.5） cmH2 O，P＜0.05]。结论 Coopdech支气管封堵器与双腔支气管导管均可用于儿童单肺通气，但支气管封堵器具有咽喉损伤较小、插管成功率较高、术野暴露较满意、气道压力低、氧合较充分的优势。

abstractsObjective To compare the application of Coopdech bronchial blocker and double lumen bronchial tube during one lung ventilation in children.Methods Forty children undergoing one lung ventilation for thoracic surgery at Shantou Central Hospital from January 2012 to June 2013, approved by hospital ethics committee,were randomized into Coopdech bronchial blocker group (group A) and double-lumen tube group ( group B ).Anesthetic management and lung isolation were performed according to a standardized protocol.Two groups of children with the intubation time ,intubation success rate ,collapse score , the frequency of postoperative hoarseness were recorded.Before and after one lung ventilation in patients of the two groups of PaCO 2 , PaO2 and airway pressure ( PAW ) changes were recorded.Results The intubation time in A was longer than those of group B ((224 ±72)vs(165 ±46) s,P<0.05), the success rate of intubation(100%vs 85%,P<0.05),collapse score in A group was higher than in group B (95%vs 75%,P<0.05 ) , Sore throat hoarseness occurred after operation in A group was lower than in B group (10%vs 35%,P<0.05),PaO2 was higher in group A after one lung ventilation for 30 min ((206 ±58)vs (148 ±63) mmHg,P<0.05), PaCO2 and PAW were lower than group B ((36 ±4)vs(45 ±7) mmHg;(21.6 ±3.2)vs(29.3 ±5.5) cmH2O,P<0.05).Conclusion The Coodech bronchial blocker provided effective surgical exposure with less throat injuries ,higher intubation success rate ,lower airway pressure in children during video-assisted thoracoscopic surgery.