摘要目的 探讨新型尿红细胞参数在不同病理类型的肾小球肾炎中的临床应用价值.方法 取肾内科经活检证实肾小球病变的患者清洁晨尿52份,用AVE-764尿液有形成分分析仪分别检测不同病理类型的原发性(39例)和继发性(13例)肾小球性肾炎患者尿液中芽孢形红细胞百分率和尿红细胞大小-形状位相图的异同.结果 原发性肾小球肾炎和继发性肾小球肾炎患者尿中均可出现芽孢形红细胞.芽孢形红细胞百分率在原发性肾小球肾炎患者中占94.1％,在继发性肾小球肾炎患者中占5.9％.肾小球肾炎患者尿红细胞大小-形状位相图可呈横条形、倒三角形、拖尾形.其中呈横条形大小-形状位相图的患者中,原发性肾小球肾炎患者占95.2％,呈倒三角形大小-形状位相图的患者全部为原发性肾小球肾炎患者,呈拖尾形大小-形状位相图的患者全部为继发性肾小球肾炎患者.结论 肾小球肾炎患者芽孢形红细胞百分率较高时常为原发性肾小球肾炎,结合尿红细胞位相图可为不同病理类型的肾小球肾炎的鉴别诊断提供一定的参考价值.

abstractsObjective To investigate the clinical value of new kinds of urinary erythrocyte morphology parameter in discriminating different pathology types of glomerulonephritis.Methods All of the 52 urine samples were from glomerulonephritis patients who had been diagnosed by renal biopsy results.The change of the percentage of acanthocytes,the size of RBC,the shape of RBC between the primary glomerulonephritis(39 cases) and secondary glomerulonephritis (13 cases)urine were detected by AVE-764 fully automatic urine cell analyzer.Results Acanthocytes could be found in both primary glomerulonephritis and secondary glomerulonephritis.Of the patients whose acanthocytes percentages above 10％,94.1％ had primary glomerulonephritis and 5.9％ had secondary glomerulonephritis.The picture of size-shape phase were classified as strip-type,inverted triangle-type and hanging tail-type.95.2％ Strip-type cases were from primary glomerulonephritis patients.Triangle-typenormally cases were all from primary glomerulonephritis patients.Hanging tail-type cases were all from secondary glomerulonephritis.Conclusion High acanthocytes percentage is most common in primary glomerulonephritis,going with the size and shape of RBC can be useful in the differential diagnosis of different pathology types of glomerulonephritis.