摘要目的 比较高原地区世居藏族与久居汉族青年男性睡眠结构及睡眠质量的差异.方法 选择海拔3 780 m地区的14名世居藏族青年男性[年龄(32.0±9.1)岁]为藏族组,出生并生活于此地区的11名久居汉族青年男性[年龄(36.6±7.6)岁]为汉族组,均进行夜间多导睡眠监测,并按照国际标准对两组之间的睡眠结构及睡眠质量进行分析与比较.结果 藏族组睡眠效率和夜间血氧饱和度均显著高于汉族组(93.1％±3.9％比85.7％±4.2％和89.4％±2.0％比84.6％±4.3％,均P ＜0.05),而觉醒指数[(1.9±0.8)比(4.1±1.3)次/h]、微觉醒指数[(23.4±5.8)比(28.7±4.1)次/h]、氧减指数[(11.7±4.8)比(16.3±7.5)次/h]、呼吸暂停低通气指数[(5.8±2.3)比(9.6±4.2)次/h]、夜间平均心率[(66.9±8.3)比(79.9±6.7)次/min]均显著低于汉族组(均P＜0.05);藏族组深睡眠时间比例较高(20.1％±7.2％比8.8％±3.3％),而汉族组非快速眼动(NREM)2期和浅睡眠时间比例较高(31.1％±11.9％比18.4％±6.7％和76.1％±11.7％比70.8％±11.2％,均P＜0.05).结论 高原地区世居藏族与久居汉族比较,有更好的睡眠结构和睡眠质量.

abstractsObjective To compare young males' sleep quality and structure between native Tibetans and longtime Han residents.Methods A total of 14 male Tibetans and 11 male Hans at an altitude of 3 780 m were enrolled in this study.Tibetans were native highlanders with a mean age of (32.0 ± 9.1) years.Han subjects were born and living in high altitude with a mean age of (36.6 ± 7.6) years.All subjects were monitored by Polysomnography (PSG),and the differences of sleep structure and quality between the two groups were compared according to the international standard.Results The sleep efficiency (93.1％ ± 3.9％ vs 85.7％ ± 4.2％) and nocturnal oxygen saturation (SpO2) (89.4％ ±-2.0％ vs 84.6％ ± 4.3％) in Tibetans was significantly higher than those in Hans (both P ＜ 0.05).The number of awakening ((1.9 ± 0.8) vs (4.1 ± 1.3)/h) and micro-awakening ((23.4 ± 5.8) vs (28.7 ± 4.1)/h),the oxygen reduction index ((11.7 ± 4.8) vs (16.3 ± 7.5)/h),apnea hypoventilation index (AHI) ((5.8 ± 2.3) vs (9.6 ± 4.2)/h) and average heart rate ((66.9 ± 8.3) vs (79.9 ± 6.7)/min) of Tibetans were significantly lower than Hans (all P ＜0.05).Tibetans had longer slow wave sleep (20.1％ ±7.2％ vs 8.8％ ±3.3％) and the Hans had longer stage 2 of non-rapid eye movement (NREM) (31.1％ ± 11.9％ vs 18.4％ ± 6.7％) and shallow sleep (76.1 ± 11.7 vs 70.8 ± 11.2) (all P ＜ 0.05).Conclusion Tibetans have better sleep quality and higher sleep efficiency than Han residents at high altitude.