摘要目的 探讨不同病理分型炎性肌纤维母细胞瘤(IMT)的CT表现,提高对本病的认识及诊断水平.方法 回顾性分析2011年2月至2015年11月郑州大学第一附属医院29例经病理证实的IMT的临床和影像资料,并结合文献资料分析总结该病的CT表现特征与病理基础,并对3种病理分型的IMT患者性别、肿瘤形态、肿瘤边界及位置(肿瘤位于头颈、胸部、腹部),分别进行x2检验.结果 29例患者年龄2 ～78岁.黏液血管型7例,梭形细胞紧密型13例,纤维型9例.免疫组化:Vimentin (22/29),SMA(28/29)为强阳性表达,ALK(4/29)及CD-67 (6/29)为部分表达,其他标志物S-100等为阴性表达.x2检验显示仅有患者的性别差异有统计学意义(P＜0.05).结论 不同病理分型IMT的CT表现及临床特征存在差异,但最终确诊仍需结合病理及免疫组化.CT检查对明确病灶范围以及与邻近结构关系有重要价值,可以指导临床选择合理的治疗方案.

abstractsObjective To explore the computed tomography (CT) features of inflammatory myofibroblastic tumor(IMT) in different pathological types,and improve the diagnostic level of this disease.Methods The CT features of 29 cases pathologically confirmed IMTs were retrospectively reviewed along with a literature review to analyze the CT features and pathological correlations,and three kinds of pathological classification of IMT in patients with gender,shape,boundary and location were respectively analyzed by Chi-Square test.Results The age ranges from 2 to 78 years.There were 7 cases of mucinous blood vessel type and 13 cases of spindle cell type and 9 cases of fiber type.Immunohistochemically,Vimentin (22/29) and SMA (28/29) were positive in all the cases,ALK (4/29) and CD-67(6/29) were partly positive expression,other markers such as S-100 were negative expression.The Chi-Square test showed that there were statistically differences in the gender of the patients.Conclusion The CT and clinical features differ according to pathological types of IMT.Its final diagnosis still needs to be combined with pathology and immunohistochemistry result.In all,CT has a role in assessing the extension of IMT and especially about the relationship with adjacent organs which can effectively direct the establishment of clinical treating scheme.