应重视净超滤率在重症患者连续性肾脏替代治疗中的应用

Attention should be paid to the application of net ultrafiltration rate in continuous renal replacement therapy for critically ill patients

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摘要连续性肾脏替代治疗（CRRT）在重症患者的容量管理中发挥着重要作用，净超滤（NUF）率作为CRRT的重要治疗参数，在重症患者容量管理中的个体化处方与作用受到广泛关注。本文梳理了CRRT的临床实践中NUF率设置与重症患者预后的关系，以期寻求NUF率的最佳治疗范围，提高CRRT容量管理效果，并为将来NUF率的研究提供一定参考。

abstractsContinuous renal replacement therapy (CRRT) plays a crucial role in the volume management for critically ill patients. Net ultrafiltration (NUF) rate, as an important therapeutic parameter of CRRT, has received widespread attention for its individualized prescription and functionin volume management of critically ill patients. The aim of this article is to identify the relationship between NUF rate settings and the prognosis of critically ill patients in the clinical practice of CRRT, determine the optimal therapeutic range of NUF rate, and thus improve the effect of CRRT volume management, and provide insights into to future NUF rate studies.

作者金璐 ^[1] 张凌 ^[1] 学术成果认领

作者单位四川大学华西医院肾脏内科　四川大学华西医院肾脏病研究所，成都　610041 ^[1]

关键词急性肾损伤连续性肾脏替代治疗净超滤率容量过负荷 Acute kidney injury Continuous renal replacement therapy Net ultrafiltration rate Fluid overload

栏目名称 专家论坛

DOI 10.3760/cma.j.cn112137-20240502-01026

发布时间 2025-02-25

基金项目

国家重点研发计划 四川省科技厅重点研发项目 四川大学华西医院学科卓越发展1.3.5工程项目 National Key Research and Development Program of China Key Projects of Research and Development of Sichuan Provincial Science and Technology Department 3.5 Project for Disciplines of Excellence from West China Hospital of Sichuan University