摘要主要探讨梅尼埃病（MD）患者眩晕发作间歇期的平衡功能特征，分析影响平衡功能的相关因素。回顾性分析2021年7月至2023年12月山东省耳鼻喉医院眩晕疾病科收治的183例MD患者的临床资料。利用感觉统合试验（SOT）测试平衡功能，检测平均听阈、半规管功能、耳石器功能及内淋巴积水情况。纳入患者男89例，女94例，年龄（46.3±9.1）岁，SOT显示有87例（47.5%）存在平衡功能障碍，分为前庭功能障碍型（58例）、视觉依赖型（13例）和视觉前庭功能障碍型（16例）。多因素logistic回归分析显示眼肌前庭诱发肌源性电位异常（ OR=1.977，95% CI：1.023~3.819）和冷热试验异常（ OR=2.310，95% CI：1.153~4.630）是平衡功能障碍的影响因素。研究提示MD患者眩晕发作间歇期的平衡功能障碍发生率较高，椭圆囊功能和水平半规管低频功能是平衡功能的影响因素。

abstractsThis study aimed to investigate the characteristics of balance function during the interictal period in patients with Ménière′s disease (MD) and analyze related influencing factors. A retrospective analysis was conducted on the clinical data of 183 MD patients admitted to the Vertigo Department of Shandong ENT Hospital between July 2021 and December 2023. Balance function was assessed using the sensory organization test (SOT), along with evaluations of mean hearing threshold, semicircular canal function, otolith organ function, and endolymphatic hydrops status. The cohort comprised 89 male and 94 female patients, aged (46.3±9.1) years. SOT results revealed balance dysfunction in 87 cases (47.5%), categorized into vestibular dysfunction type (58 cases), visual dependence type (13 cases), and visual-vestibular dysfunction type (16 cases). Multivariate logistic regression analysis identified abnormal ocular vestibular evoked myogenic potentials ( OR=1.977, 95% CI: 1.023-3.819) and abnormal caloric test results ( OR=2.310, 95% CI: 1.153-4.630) as significant influencing factors for balance dysfunction. This study suggests a high prevalence of balance dysfunction during the interictal period in MD patients, with utricular function and low-frequency horizontal semicircular canal function being key determinants of balance performance.