摘要神经血管压迫是典型性三叉神经痛的主要病因，显微血管减压术通过解除责任血管对三叉神经的压迫可使患者获得临床治愈。而缘于多发性硬化、肿瘤等原发性神经系统疾病的继发性三叉神经痛以及病因不明的特发性三叉神经痛具有与典型性三叉神经痛不同的病因、诊断及治疗原则。由于国内外缺乏此类三叉神经痛的规范化诊疗指南，其诊断与分类不明、治疗效果差及并发症多等一系列问题在临床上多见，并引起大量专家重视。因此，中国医师协会神经修复学专业委员会、中国医师协会周围神经外科专业委员会及国际神经修复委员会联合国内25家医疗中心的神经外科、疼痛科专家，在最新循证医学证据及多学科临床经验的支撑下围绕其诊断、鉴别诊断、影像学检查、药物治疗及手术治疗等方面系统制订了19条推荐意见，旨在规范三叉神经痛的临床诊疗。

abstractsNeurovascular compression is the primary etiology of classical trigeminal neuralgia. Microvascular decompression can achieve clinical cure by relieving the compression of responsible blood vessels on the trigeminal nerve. However, secondary trigeminal neuralgia caused by primary neurological diseases such as multiple sclerosis and tumors, as well as idiopathic trigeminal neuralgia with unclear etiology, exhibit distinct pathogenesis, diagnostic criteria, and treatment principles compared to classical trigeminal neuralgia. Due to the lack of standardized diagnostic and therapeutic guidelines for these types of trigeminal neuralgia internationally, clinical practice often faces issues such as unclear diagnosis and classification, poor treatment outcomes, and frequent complications, which have drawn significant attention from experts. Therefore, the Specialized Committee on Neurorestoratology of Chinese Medical Doctor Association, Specialized Committee on Peripheral Nerve Surgery of Chinese Medical Doctor Association, and International Association of Neurorestoratology, in collaboration with experts from neurosurgery and painology departments across 25 domestic medical centers, systematically developed 19 recommendations based on the latest medical evidence and multidisciplinary clinical experience. These recommendations address diagnosis, differential diagnosis, imaging examinations, pharmacological treatment, and surgical interventions, aiming to standardize the clinical management of trigeminal neuralgia.