炎症性肠病消化道肿瘤的发生风险与监测
Risk and surveillance of gastrointestinal tumors in patients with inflammatory bowel disease
摘要炎症性肠病(IBD)是一组病因不明的肠道慢性非特异性炎性疾病。IBD的慢性炎症状态累及整个胃肠道,其发生结直肠癌和小肠癌等消化道肿瘤的风险明显增加,严重影响预后。随着我国IBD的患病率逐渐升高,IBD相关消化道肿瘤的防治仍然是临床医生面临的重大挑战。对IBD患者消化道肿瘤的发生风险进行危险分层从而制定个体化监测策略具有重要意义。生物标志物的开发、内镜方法和活检方式的选择均是未来研究的方向。本文就IBD消化道肿瘤的流行病学、危险因素、生物标志物和内镜监测作一论述。
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abstractsInflammatory bowel disease (IBD) is a group of intestinal chronic non-specific inflammatory diseases with unknown etiology. The chronic inflammatory state of IBD affects the whole gastrointestinal tract, which significantly increases the risk of colorectal cancer, small bowel cancer and other gastrointestinal tumors, and seriously affects the prognosis of IBD patients. With the increasing prevalence of IBD in China, the prevention and treatment of IBD associated gastrointestinal tumors is still a major challenge for clinicians. It is of great significance to stratify the risk of gastrointestinal tumors in IBD patients so as to develop individualized surveillance strategies. The development of biomarkers and the selection of endoscopic methods and biopsy methods are the directions of future research. This article reviews the epidemiology, risk factors, biomarkers and endoscopic surveillance of gastrointestinal tumors in IBD.
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