肝病临床诊治需求与实验室检测技术进展
Requirement of diagnosis and tereatment for liver diseases and improvement of laboratory technology
摘要我国是肝病大国,肝病的诊治直接关系我国全民健康水平.肝病临床诊治对实验室检测的需求可以归纳为:(1)敏感,即缩短检测窗口期;(2)特异,即识别各亚型和变异株;(3)快速,即尽快确定病原;(4)准确,即为临床提供可靠检测结果.以化学发光技术、PCR技术和基因突变位点检测技术等为代表的检测技术应用于肝病诊治中,在精密度、准确度、灵敏性、特异性和检测速度等方面得到了大大提升,最大限度地满足了肝病的临床诊治需求.
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abstractsThere are so many patients with different liver diseases in our country that the diagnosis and treatment of liver diseases directly relate to the people's healthy level.The requirement of diagnosis and treatment to clinical laboratories can be summarized as: ( 1 ) sensitivity,which means shortening window period;(2) specificity,which means various subtypes and variant can be detected;( 3 )speed,which means finding out the pathogen as soon as possible;(4)accuracy,which means providing physicians with accurate test reports.Detecting techniques,for instances,chemiluminescence,polymerase chain reaction and gene mutational site detecting method,were applied to the diagnosis and treatment of liver disease,thus improving the degree of precision,accuracy,sensitivity,specificity and detection speed and satisfying the requirement of diagnosis and treatment maximatily.
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