摘要目的:建立积极、有效的科研课题申报管理模式，促进医院科研能力提高。方法:回顾性分析上海交通大学医学院附属新华医院2010—2019年期间获得国家级及省部级科研课题的资助情况，评价"点对点"科研课题申报管理模式的实践效果。结果:通过多维度实施"点对点"科研课题申报管理模式，近10年医院课题获资助情况，尤其是国家级科研课题与省部级科研人才项目获资助情况明显提升，国家级课题从2010年获34项(2 602万元)发展到2019年获72项(5 108.51万元)；省部级人才项目从2010年5项(105万元)增长至2019年26项(650万元)。结论:"点对点"科研课题申报管理模式对科研课题资助整体情况发挥较好的促进作用，进一步探索完善该模式，利用"紧密型搭档"实体早启动、重部署，引进与培养科研人才，从而提升医院科研综合实力。

abstractsObjective:To establish a supportive and effective management mode of scientific research project application, promote the capacity building of scientific research in the hospital.Methods:Retrospective analysis was conducted on the national and provincial scientific research projects of Xinhua Hospital Affiliated to Shanghai Jiaotong University Medical School from 2010 to 2019, and the practical effect of " point to point" management mode of scientific research project application was evaluated.Results:The funding rate of Xinhua Hospital, especially national scientific research projects and provincial talents projects, was greatly improved by adoption of the multi-dimensional " point to point" management mode of scientific research project application. The number of national scientific research projects increased from 34 (26.02 million) in 2010 to 72 (51.0851 million) in 2019.The number of provincial talents projects increased from 5 (1.05 million) in 2010 to 26 (6.5 million) in 2019.Conclusions:The " point to point" management mode of scientific research project application plays an important role in promoting the overall funding rate. Enhancement of comprehensive capacity of hospital scientific research can be achieved by further improvement of this management mode, early initiation and arrangement of funding application depending on the " close partner" entity, emphasizing scientific research talents cultivation.