摘要目的 探索应用计算机辅助设计/计算机辅助制造(CAD/CAM)技术制造的钛合金补片修复大面积颅骨缺损的方法.方法 2006年4月至、2008年6月期间,收治因肿瘤和外伤所致颅骨大面积缺损患者7例,采集电子计算机断层扫描(CT)数字化图像数据,利用快速成型技术制作患者的颅骨树脂漠型,应用铸造技术制备修复颅骨缺损的钛合金.结果 制造出个性化的颅骨树脂模型和精密的钛合金补片,置入体内,紧密覆盖颅骨缺损区.术后7例患者伤口均Ⅰ期愈合,随访6个月至1年,缺损区颅骨外形恢复满意.结论 利用CAD/CAM技术加工出的钛合金补片可以修复颅骨的大面积缺损,获得理想的修复效果.该方法操作简单,修复精确,很高的临床应用价值.

abstractsObjective To explore a method of large cranial bone defect reconstructed by titanium implant with computer aided design(CAD)/computer aided manufacture(CAM)technique.Methods From April 2006 to June 2008,7 cases of cranial bone defect due to tumor and trauma were admitted.The data of skull bone defects were obtained by CT.The resin model was designed and manufactured with rapid prototyping technique.Results The CT data could be used by image software directly.The resin model was manufactured accurately by RP technique.The titanium implant design could be completed by CAD/CAM.7 patients achieved one stage healing.After a follow-up of 6 months to 1 year,cranial bone defect was reconstructed satisfactorily.Conclusion Individual design and repair of large cranial bone defect with CAD/CAM technique is worth extending application clinically.It is a quite ideal and very simple method for the surgical treatment of the cranial bone defect.