摘要目的 评价不同类型激光治疗寻常痤疮的疗效和安全性,以便为临床应用选择最佳方案提供依据.方法 采用Cochrane系统评价的方法,计算机检索Medline、Embase、Cochrane对照实验注册资料库、中国生物医学文献数据库、中文科技期刊数据库、中国期刊全文数据库,检索时间截至2009年6月,纳入中英文激光治疗寻常痤疮的随机对照实验(RCT).结果 共纳入符合标准的论文12篇,临床治疗367例,由于缺乏临床同质性,只能进行描述性分析.各型激光治疗寻常痤疮,炎症性皮损计数改善明显,不良反应限于治疗部位的暂时性红斑水肿及可以耐受的与治疗相关的疼痛.结论 各型激光治疗寻常痤疮安全、有效、便利.有局部不良反应.需进行更多高质量、大样本的随机对照实验,以证实激光治疗寻常痤疮的作用和地位.

abstractsObjective To assess the efficacy and safety of various spectrum lasers in the treatment of acne vulgaris. Methods Based on the principles and methods of Cochrane systematic reviews, we searched the Cochrane Library (2009, 6 issues), PubMcd, Embase, China Biomedical Literature Database, China Journal Full Text Database, Chinese Scientific Journals Full Text Database. Retrieval time was up to June, 2009. Randomized controlled trials (RCTs) of lasers for acne vulgaris were included. Results Twelve RCTs totaling 367 patients were included. Because the lack of clinical homogeneity, only descriptive analysis was conducted. Acne lesion counts improved significantly with laser therapy. Adverse effects were limited to transient erythema and edema at treatment sites. Treatment-related pains were well tolerated. Conclusions Current evidence demonstrates that all type lasers in treating acne vulgaris is safe and efficacy. However, higher quality RCT research would be needed to verify the effects and status of lasers on acne vulgaris.