摘要目的 探讨低能量1064 nm调Q激光联合强脉冲光(IPL)治疗继发性色素沉着的疗效和可行性.方法 将128例继发性色素沉着患者依据不同治疗方式,完全随机分为低能量1064 nm调Q激光治疗组(42例),强脉冲光治疗组(40例),低能量1064 nm调Q激光联合强脉冲光治疗组(46例).比较3组的治疗效果.结果 通过6次治疗,强脉冲光组和调Q激光组的有效率分别为50.0％(20/40)、52.4％(22/42),两组治疗结果比较差异无统计学意义(P＞0.05);低能量1064 nm调Q激光联合强脉冲光疗组有效率为73.9％(34/46),与强脉冲光和调Q激光治疗组比较,差异有统计学意义(P＜0.05).结论 低能量1064 nm调Q激光联合强脉冲光是面部继发性色素沉着有效的治疗方法,并且安全无明显不良反应.

abstractsObjective To study the feasibility of joint phototherapy in the treatment of post-inflammatory hyperpigmentation and non-drug therapy in clinical popularization value of 1064 nm Qswitched laser in combination with low energy intense pulsed noncoherent light for secondary pigmentation.Methods A total of 128 patients with post-inflammatory hyperpigmentation were randomly divided into 3 groups according to different treatments:first group (42 cases) was subjected to low energy 1064 nm Q-switched laser treatment;second group (40 cases) had intense pulsed light treatment;third group (46 cases) had low energy 1064 nm Q-switched laser plus intense pulsed light therapy.Results After treating for 6 times,the effective rates of intense pulsed light and Q laser were 50％ (20/40) and 52.4％ (22/42),respectively,without statistical significance between two groups (P＞0.05).Effective rate of the third group was 73.9％ (34/46),with significant difference (P＜0.05),compared with the first two groups.Conclusions For those who refuse any drug treatment,low energy 1064 nm Q-switched laser with intense pulsed light therapy is an effective option to facial postinflammatory hyperpigmentation.Furthermore,it has obvious and safe effect without complications and deserves popularization.