摘要目的 探讨面部自体脂肪颗粒注射移植联合A型肉毒毒素注射进行面部轮廓重塑的临床效果.方法 以吸脂针接注射器负压抽吸大腿内侧或腹部脂肪颗粒,静置分层,排出下层水分,漂洗,提取黄色脂肪颗粒转入2 ml注射器,多点、多隧道、多层次注射到面部凹陷区域,每次过枉矫正注射20％～30％.共对89例患者进行了注射,其中行2次注射者,颞部13例(14.6％),额部16例(17.98％).其中30例皮下注射A型肉毒毒素,每侧小于20 U.结果 随访3～36个月,额颞部轮廓及皮肤质地均可见明显改善,脂肪颗粒成活率达60％～80％.无血肿、硬结、感染等并发症发生.联合A型肉毒毒素注射的患者面部轮廓加强,满意度高.结论 自体脂肪颗粒注射移植于面部,临床效果稳定,联合A型肉毒毒素皮下注射后面部轮廓加强,是面部年轻化及轮廓重塑的一种安全、理想的方法.

abstractsObjective To discuss the clinical effect of facial contour remodeling using transplantation of the autologous granular fat grafting combined with botulinum toxin A injection.Methods Negative-pressure liposuction was carried out in the inner thigh or abdomen using liposuction needle connected with an injector,to let stand for layered,discharge lower layer water,rinse,extract the fat particles into a 2 ml syringe,inject into facial depression area with multipoint,multiple-tunnel,and multilayer manner,over injection of about 20％-30％ every time.89 patients received the injection;some accepted two injections;13 cases were injected in temple (14.6％),and 16 in forehead (17.98％).30 of them received subcutaneous injection of botulinum toxin A,each side dose was less than 20 U.Results Patients had been followed up for 3-36 months,and obvious improvements were observed in facial contour in the frontal and temporal region as well as the skin texture;the survival rate of fat granule reached to 60％-80％.No hematoma,nodes and infection been observed.Patients combined with botulinum toxin A injection had more ideal facial contour and more satisfaction.Conclusions Autologous fat granules transplantation in the face has stable clinical effect,and combining with botulinum toxin A injection can improve facial contour.It is a safe,ideal treatment in facial rejuvenation and facial contour remodeling and it therefore can be widely recommended in clinical treatment.