摘要肺癌是中国发病率和死亡率最高的恶性肿瘤。2022年中国肺癌新发病例约106.06万例，死亡约73.33万例。肺癌患者脑转移发生率高、预后差、自然生存期短。近年来，随着外科手术、放射治疗和内科治疗等治疗水平的不断提高，肺癌脑转移患者的治疗选择越来越多，生存时间得以延长。为了及时反映国内外肺癌脑转移治疗的新进展，进一步提高中国肺癌脑转移患者的规范化治疗水平，在《肺癌脑转移中国治疗指南（2021年版）》基础上，中国医疗保健国际交流促进会肿瘤内科学分会和中国医师协会肿瘤医师分会组织专家编写了《肺癌脑转移中国治疗指南（2026版）》，对指南方法学、流行病学数据、临床表现、辅助检查、外科手术治疗、放射治疗、2025年8月31日之前获得中国国家药品监督管理局批准上市的新药、新治疗方案和新适应证等方面进行了系统、全面地更新，增加了治疗推荐意见和推荐级别，涵盖了肺癌脑转移患者诊治过程中常见的临床问题，以便更好地为肺癌脑转移患者的规范化治疗提供帮助。

abstractsLung cancer is the leading malignancy in China in terms of both incidence and mortality, with an estimated 1.06 million new cases and 733,300 related deaths in 2022. Lung cancer patients have a high incidence of brain metastases, which are associated with poor prognosis and short natural survival period. In recent years, with continuous advances in surgery, radiotherapy and systemic therapies, treatment options for lung cancer patients with brain metastases have expanded, leading to prolonged survival. To promptly reflect the latest progress in the treatment of lung cancer with brain metastases worldwide and to further promote standardized treatment in China, the Medical Oncology Branch of China International Exchange and Promotive Association for Medical and Health Care and the Chinese Association for Clinical Oncologists organized experts to formulate "China clinical practice guideline for brain metastases of lung cancer (2026 edition)", on the basis of "Clinical practice guideline for brain metastases of lung cancer in China (2021 version)". The updated guideline provides systematic and comprehensive revisions on methodology, epidemiological data, clinical manifestations, auxiliary examinations, surgical management, radiotherapy, new drugs, new treatment regimens, and new indications approved by the China National Medical Products Administration before August 31, 2025. It also incorporates treatment recommendations with corresponding levels of evidence and grades of recommendation, covering common clinical issues in the diagnosis and management of lung cancer patients with brain metastases, thereby offering better practical guidance for standardized patient care.