摘要目的 探究皮肤软组织扩张术一期术后感染发生的独立危险因素,为降低感染率提供指导.方法 收集西京医院整形外科2003年1月至2012年12月间行扩张器置入术的2056例次患者3382枚扩张器临床资料,应用单因素Logistic回归法进行比较,将P<0.1的潜在危险因素引入多因素Logistic回归分析模型,采用Backward Conditional法行逐步回归分析,以P<0.05筛选出独立危险因素.结果 3382枚扩张器,一期术后发生感染的177枚,发生率为5.2％(177/3382).经过统计分析最终发现术前白细胞较低、年龄大、扩张器同时置入数增加、扩张器容积增高是感染发生的独立危险因素(P<0.05).结论 术前白细胞计数越低、年龄越大、单次手术扩张器埋置数越多、扩张器容积越大时,软组织扩张术后发生感染的可能性越大.

abstractsObjective The incidence of complications after skin soft tissue expansion is relatively high. Occurrence of infection often means the expander has to be taken out ahead of schedule. In this retrospective study, we wanted to identify independent risk factors of infection after skin soft tissue expansion, which could be helpful to guide clinical work. Methods Demographic information of patients who underwent the skin soft tissue expansion at the department of plastic surgery of Xijing Hospital from January 2003 to December 2012 was collected. Univariate associations with infection were measured by logistic regression and represented as odds ratios. The p-value less than 0.1 was identified the potential risk factor. Multivariate logistic regression was used to calculate odds ratios for risk factors of infection. Independent risk factors were identified if the p-value was less than 0. 05. Results A total of 3382 implants were included in the study. The overall infection rate of tissue expansion was 5. 2％ in 177 implants. The result of multivariate logistic regression showed that preoperative white blood cell count, age, numbers of expander implanted and volume of expander were independent risk factors of infection. Conclusions Independent risk factors of infection were preoperative white blood cell count, age, numbers of expander implanted and volume of expander. The lower preoperative white blood cell count, age more than 18 years old, more numbers of expander implanted and the bigger volume of the expander, the higher possibility of complications occurred. The result was helpful to guide clinical work and reduce the incidence of infection.