摘要目的:为成都地区正常青年汉族人群上唇相关指标三维测量数据库的建立进行先期调查，并建立参考数值。方法:采用随机数字表抽样法纳入2012年9月至2019年12月于四川省人民医院就诊的志愿者。分别收集其面部多层螺旋CT(MSCT)资料，获取影像数据生成三维模型，并使用3-matic Medical 13.0软件进行分析，对上唇相关线性指标[人中切迹点-唇珠最低点(Ls-Sto)、唇珠最低点-下唇红唇缘中点(Sto-Li)、鼻唇点-唇珠最低点(Sn-Sto)、鼻唇点-人中切迹点(Sn-Ls)、人中切迹点-下唇红唇缘中点(Ls-Li)、右侧唇峰点-左侧唇峰点(CphR-CphL)、右侧口角点-左侧口角点(ChR-ChL)、右侧人中嵴中点-左侧人中嵴中点(MphR-MphL)、右侧鼻翼基底点-左侧鼻翼基底点(SbalR-SbalL)、唇珠最低点-颏唇沟点(Sto-Sl)]、比例指标[人中切迹点-唇珠最低点/唇珠最低点-下唇红唇缘中点(Ls-Sto/Sto-Li)、右侧人中嵴中点-左侧人中嵴中点/右侧口角点-左侧口角点(MphR-MphL/ChR-ChL)、右侧人中嵴中点-左侧人中嵴中点/右侧唇峰点-左侧唇峰点(MphR-MphL/CphR-CphL)、人中切迹点-唇珠最低点/鼻唇点-唇珠最低点(Ls-Sto/Sn-Sto)、唇珠最低点-下唇红唇缘中点/唇珠最低点-颏唇沟点(Sto-Li/Sto-Sl)]，以及鼻唇角角度进行测量，并采用唇珠—双侧口角三点拟合圆法对上唇弧度进行测量，包括右侧口角点-人中切迹点-左侧口角点(ChR-Ls-ChL)、右侧人中嵴中点-鼻唇点人中切迹点中点-左侧人中嵴中点(MphR-A-MphL)、右侧鼻翼基底点-鼻唇点-左侧鼻翼基底点(SbalR-Sn-SbalL)。采用 t检验比较不同性别、年龄(18~24、25~30岁)上述指标的差异，对于不同弧度位置指标的比较采用方差分析及SNK- q法进行分析。 结果:本研究共纳入150名志愿者，其中男性68名(45.3%)，女性82名(54.7%)，年龄为18~30岁，平均24岁。(1)不同性别之间比较：线性指标中Ls-Sto、Sto-Li、Sn-Sto、Sn-Ls、Ls-Li、CphR-CphL、ChR-ChL、SbalR-SbalL、Sto-Sl的差异具有统计学意义( P<0.05)，MphR-MphL差异无统计学意义( P>0.05)；比例指标中Ls-Sto/Sn-Sto、Sto-Li/Sto-Sl的差异有统计学意义( P<0.01)，Ls-Sto/Sto-Li、MphR-MphL/ChR-ChL、MphR-MphL/CphR-CphL的差异无统计学意义( P>0.05)。鼻唇角差异无统计学意义( P>0.05)；弧度指标中ChR-Ls-ChL差异具有统计学意义( P<0.05)，MphR-A-MphL、SbalR-Sn-SbalL差异无统计学意义( P>0.05)。(2)不同年龄组之间比较：各个线性指标、比例指标、鼻唇角、弧度指标差异均无统计学意义( P>0.05)。(3)不同弧度位置之间比较：3个不同弧度位置的弧度值比较差异具有统计学意义( P<0.01)，ChR-Ls-ChL分别与MphR-A-MphL、SbalR-Sn-SbalL比较差异有统计学意义( P<0.01)，MphR-PoinA-MphL与SbalR-Sn-Sbal之间差异无统计学意义( P>0.05)。 结论:该研究基于MSCT影像资料完成了成都地区正常青年汉族人群上唇相关指标三维测量数据的先期调查，并建立了参考值，可通过获得的数据集为临床评估、设计提供直观的参考资料。此外，通过测量上唇的弧度评估上唇是一种新的测量方法，能有效地反映上唇的生理弧线。

abstractsObjective:To conduct a preliminary investigation on the establishment of a three-dimensional measurement database of upper lip-related indicators in the normal young Han population in Chengdu, and to establish reference values.Methods:A simple random sampling method was used to recruit 150 volunteers who visited Sichuan Provincial People’s Hospital between September 2012 and December 2019. The facial multi-slice spiral CT (MSCT) data were collected, and the image data was obtained to generate a three-dimensional model, which was analyzed by applying 3-matic Medical 13.0 software. The linear and proportional indices of upper lip correlation were measured including the crista philtra, right side point-the crista philtra, left side point (CphR-CphL), the right cheilion point- the left cheilion point (ChR-ChL), the middle point of crista philtra, right side point-the middle point of crista philtra, left side point (MphR-MphL), the apex of philtral column, right side point-the apex of philtral column, left side point(SbalR-SbalL), the stomion point-the sublabiale point (Sto-Sl)], ratio index [Ls-Sto/Sto-Li, MphR-MphL/ChR-ChL, MphR-MphL/CphR-CphL, Ls-Sto/Sn-Sto, Sto -Li/Sto-Sl]. In addition, the angle of the nasolabial angle was measured, and the radian of the upper lip was measured by the lip bead-bilateral angle three-point fitting circle method. The t test was used to compare the differences of the above indicators in different genders and ages (18-24, 25-30 years old). For the ChR-Ls-ChL, the Mphr-the middle point of subnasale and labrale-mphl(MphR-A-MphL), the SbalR-Sn-SbalL different radian position indexes were compared by ANOVA and SNK- q method. Results:A total of 150 volunteers were included in this study, including 68 males (45.3%) and 82 females (54.7%), ranging in age from 18 to 30 years old, with an average age of 24 years. Between different genders: the differences in linear indicators Ls-Sto, Sto-Li, Sn-Sto, Sn-Ls, Ls-Li, CphR-CphL, ChR-ChL, SbalR-SbalL, Sto-Sl were statistically significant ( P<0.05), there was no significant difference in MphR-MphL ( P>0.05); there were significant differences in Ls-Sto/Sn-Sto, Sto-Li/Sto-Sl in the ratio indicators ( P<0.01), Ls -Sto/Sto-Li, MphR-MphL/ChR-ChL, MphR-MphL/CphR-CphL had no significant difference ( P>0.05). There was no significant difference in nasolabial angle ( P>0.05); the difference in radian index ChR-Ls-ChL was statistically significant( P<0.05), there was no significant difference in MphR-A-MphL, SbalR-Sn-SbalL in radian index ( P>0.05). Between different age groups: there was no significant difference in each linear index, proportional index, angle index and radian index. ( P>0.05) Between different radian positions: the radian values of 3 different radian positions were significantly different ( P<0.01). ChR-Ls-ChL was compared with MphR-A-MphL, SbalR-Sn-SbalR the difference in SbalL was statistically significant ( P<0.01), but there was no significant difference between MphR-PoinA-MphL and SbalR-Sn-Sbal ( P>0.05). Conclusions:Based on the MSCT image data, this paper completed the preliminary survey of the three-dimensional measurement database of the upper lip-related indexes of the normal young Han population in Chengdu area, and established the reference value. The obtained data set can provide an intuitive reference for clinical evaluation and design. In addition, evaluating the upper lip by measuring the curvature of the upper lip is a new measurement method that can effectively reflect the physiological curvature of the upper lip.