换一批摘要The binding of pefloxacin mesylate (PFLX) to bovine lactoferrin (BLf) and human serum albumin (HSA) in dilute aqueous solution was studied using fluorescence spectra and absorbance spectra. The binding constant K and the binding sites n were obtained by fluorescence quenching method. The binding distance r and energy-transfer efficiency E between pefloxacin mesylate and bovine lactoferrin as well as human serum albumin were also obtained according to the mechanism of Forster-type dipole-dipole nonradiative energy-transfer. The effects of pefloxacin mesylate on the conformations of bovine lactoferrin and human serum albumin were also analyzed using synchronous fluorescence spectroscopy.
更多相关知识
关键词
Pefloxacin mesylate (PFLX)Bovine lactoferrin (BLf)Human serum albumin (HSA)Fluorescence spectraEnergy-transfer efficiency
分类号
O657.3
栏目名称
发布时间
2006-06-22（万方平台首次上网日期，不代表论文的发表时间）
基金项目
中国科学院项目（非规范项目）（20173050）
- 浏览66
- 被引3
- 下载0
相似文献
- 中文期刊
- 外文期刊
- 学位论文
- 会议论文
