摘要Type 1 diabetes(T1D)is a T lymphocyte-mediated autoimmune disease caused by pancreatic β-cell de-struction,which eventually leads to reduced insulin level and increased blood glucose level(Syed,2022).As a multifactorial disease,T1D is characterized by a genetic predisposition associated with various envir-onmental and cellular elements(Syed,2022).
作者单位Department of Pathology,the Second Xiangya Hospital,Central South University,Changsha 410011,China[1]School of Basic Medicine,Health Science Center Hubei University of Arts and Science,Xiangyang 441053,China;Guangxi Key Laboratory of Diabetic Systems Medicine,Guilin Medical University Guilin 541199,China[2]Medical Education Department,Guangdong Provincial People's Hospital,Zhuhai Hospital(Jinwan Central Hospital of Zhuhai),Zhuhai 519041,China[3]Institute of Cardiovascular Disease,Key Laboratory for Arteriosclerology of Hunan Province,Hunan International Scientific and Technological Cooperation Base of Arteriosclerotic Disease,Department of Bioinformatics and Medical Big Data,Hengyang Medical School,University of South China,Hengyang 421001,China[4]
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