摘要目的 分析乳腺钼靶X线检查数据,间接评估山西省乳腺癌发病趋势.方法 回顾性分析2005年至2007年在山西省肿瘤医院放射科进行乳腺钼靶X线检查患者的资料.对乳腺癌及良性乳腺疾病的诊断数目、比例、年龄分布、两侧乳腺癌分布和乳腺癌病理组织类型进行总结.结果 2005年至2007年,行乳腺钼靶X线检查的患者从533例增加到1975例.诊断为乳腺癌的患者由62例快速增长至400例.乳腺癌患者占所有行乳腺钼靶X线检查的患者人数的比例有增长趋势(2005年、2006年、2007年分别为11.6%、17.8%、20.3%,P<0.001).乳腺癌患者的平均年龄显著大于良性患者(49.98岁和42.8岁,P<0.001).乳腺癌阳性率最高人群为45岁至54岁年龄组(37.6%).左侧乳腺发病率大于右侧(53.42%和45.98%).大多数病理组织类型为浸润性导管癌(78.95%);浸润性小叶癌和导管原位癌分别为8.7%和5.39%.结论 乳腺癌发病率呈增长趋势,其流行病学特点与先前有关中国女性乳腺癌发病情况的研究相一致.建立乳腺癌注册制度和系统完整的乳腺疾病数据库,将为推测未来乳腺癌发病率、癌谱变化规律以及评估乳腺癌的防治效果提供科学的依据.

abstractsObjective To evaluate this disease' s incident trend for Shanxi province through hospital-based statistics. Methods Breast cancer data was obtained from the department of radiology in Shanxi cancer hospital for the period 2005-2007. Results Between 2005 and 2007, the numbers of women who accepted mammography rapidly increased from 533 to 1975. 62 women had been diagnosed as breast cancer in 2005, while this number had reached to 400 in 2007. The proportion of breast malignancies during this three year periods had statistically increased with 11.6 %, 17.8 %, and 20.3 % respectively (P<0.001). The mean age of breast cancer patients was older than benign disease patients (50 vs 42.8, P<0.001). The highest breast cancer age group was those aged 45 to 54 (37.6 %). Left breast cancer was higher than right side (53.4 % vs 46 %). Most histological type was invasive ductal carcinoma (78.95 %). The proportion of invasive lobular carcinoma and duetal carcinoma in situ were 8.7 % and 5.4 % respectively. Conclusion Breast cancer incidence rate has been increased in our city. These results are consistent with previous similar studies. Thus, it is essential to establish population cancer incidence registration and develop clinical data system. This will result in better understanding of cancer incidence trends and benefit in the evaluation of the effective cancer control measures.