换一批Effects of Overexpression of the Endogenous Farnesyl Diphosphate Synthase on the Artemisinin Content in Artemisia annua L.
摘要Artemisinin Is a novel effective antimalarial drug extracted from the medicinal plant Artemisia annua L. Owing to the tight market and low yield of artemislnin, there is great interest in enhancing the production of artemisinin.In the present study, farnesyl dlphosphate synthase (FPS) was overexpressed in high-yield A. annua to increase the artemislnin content. The FPS activity in transgenic A. annua was two- to threefold greater than that in non-transgenic A. annua. The highest artemisinin content in transgenic A. annua was approximately 0.9% (dry weight), which was 34.4% higher than that in non-transgenic A. annua. The results demonstrate the regulatory role of FPS in artemisinin biosynthesis.
更多相关知识
- 浏览146
- 被引54
- 下载0
相似文献
- 中文期刊
- 外文期刊
- 学位论文
- 会议论文
