摘要Jasmonates(JAs)are phytohormones that finely regulate critical biological processes,including plant development and defense.JASMONATE ZIM-DOMAIN(JAZ)proteins are crucial transcrip-tional regulators that keep JA-responsive genes in a repressed state.In the presence of JA-Ile,JAZ repressors are ubiquitinated and targeted for degradation by the ubiquitin/proteasome system,allowing the activation of downstream tran-scription factors and,consequently,the induction of JA-responsive genes.A growing body of evi-dence has shown that JA signaling is crucial in defending against plant viruses and their insect vectors.Here,we describe the interaction of C2 proteins from two tomato-infecting geminiviruses from the genus Begomovirus,tomato yellow leaf curl virus(TYLCV)and tomato yellow curl Sardinia virus(TYLCSaV),with the transcriptional repressor JAZ8 from Arabidopsis thaliana and its closest orthologue in tomato,SlJAZ9.Both JAZ and C2 proteins colocalize in the nucleus,forming dis-crete nuclear speckles.Overexpression of JAZ8 did not lead to altered responses to TYLCV in-fection in Arabidopsis;however,knock-down of JAZ8 favors geminiviral infection.Low levels of JAZ8 likely affect the viral infection specifically,since JAZ8-silenced plants neither display ob-vious developmental phenotypes nor present dif-ferences in their interaction with the viral insect vector.In summary,our results show that the geminivirus-encoded C2 interacts with JAZ8 in the nucleus,and suggest that this plant protein exerts an anti-geminiviral effect.