摘要1 Introduction Wet cupping therapy (WCT) is a uaditional complementary therapy,which has been in use for many centuries.WCT is used as an alternative and complementary medicine in the treatment of low back pain,migraine headaches,hypertension,brachialgia,carpal tunnel syndrome,oxygen saturation in smokers with chronic obstructive pulmonary disease and metabolic syndrome.[1] WCT is also used in dermatological diseases,such as psoriasis,atopic dermatitis acne and urticaria.[2] Side effects of WCT,such as hypotension and bradycardia,rarely occur during application.However,dermatitis,localized infection,scarring and abscess have been reported following WCT.[3] In some cases,bubbles of fluid may form at the treatment sites of WCT;these deposits may be located in the epidermis only or in both the epidermidis and the dermis.Fluid deposits of ＜ 5 mm in diameter are defined as vesicles and when diameter of fluid deposits ＞ 5 mm,they are called bullae.[4] Here we present a case of vesiculobullous lesions after WCT and discuss the physiopathology.