摘要目的 探讨CT导引下经皮穿刺 125I放射性粒子植入治疗中晚期肺癌的近期疗效及安全性.方法 对36例中晚期肺癌患者,应用治疗计划系统(TPS)计算剂量,CT定位下行肿瘤内 125I放射性粒子植入术.于术后1、3、6个月定期复查胸部CT.结果 术后1、3、6个月随访,有效率分别为88.89%、91.66%、88.89%;术后有6例发生少量气胸,未给予特殊处理3～5d后自行消失;5例术后咳少量血痰,给予止血药物后3～5d消失;无一例出现感染和癌灶种植等并发症.结论 CT引导下经皮穿刺 125I粒子植入治疗肺癌定位准确、操作简单安全、近期疗效确切.

abstractsObjective To explore the short-term curative effect and safety of CT-guided percutaneous implantation of 125I seeds in treating lung cancer. Methods Thirty-six patients with metaphase or terminal lung cancer had been analyzed.All patients were evaluated with TPS(treatment plan system)preoperatively and the post-operative quality was verified.Thirty-six cases were treated with CT-guided interstitial implantation of 125I radioactive seeds.After the implantation,CT scan was performed again after operation for 1,3 and 6 months respectively. Results The effective power was 88.89%,91.66%,88.89% respectively after 1,3 and 6 months.Pneumothorax had happened in 6 patients and it had disappeared automatically within 3-5 days.Manipulus hemoptysis had happened in 5 patients and it had been cured after using hemostatic medicine 3-5 days later.The complications of infection and cancer planting had not occured. Conclusions CT-guided interstitial implantation of 125I seeds is a safe and simple method for lung cancer with few complications and good short-term outcomes.