摘要目的 对以运动障碍起病的癌性周围神经病患者的临床特点进行分析,提高早期诊断率.方法 收集我院2005年至今临床诊断的以运动障碍起病的癌性周围神经病患者,对其临床特点、辅助检查结果进行分析.结果 共收集病例7例,均以运动障碍就诊,平均发病年龄(59±17)岁,脑脊液检查显示蛋白正常或轻度增高,肌电图检查显示神经源性损害.结论 对中老年以运动障碍起病的亚急性或慢性周围神经病,用常见周围神经病原因不能解释时应进行全面检查以发现潜在的肿瘤.

abstractsObjective To improve the early diagnostic accuracy by clinical study of paraneoplastie peripheral neuropathy with onset of weakness. Methods The patients with paraneoplastic peripheral neuropathy with onset of weakness were included since 2005 in our hospital,and their clinical features and examinations were analyzed. Results Seven cases with predominant weakness of limbs were included,with mean age(59±17)years.CSF examination showed normal or slightly increased protein level.Electrophysiological examination implied a primary damage restricted to the peripheral nerve. Conclusions The onset of middle age with movement disorders and sub-acute or chronic peripheral neuropathy,peripheral neuropathy with a common cause can not be explained should be overhauled to identify potential tumor.