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系统性淋巴结清扫术治疗子宫内膜癌疗效及近期生存率观察

Efficacy of systematic lymphadenectomy on endometrial cancer and recent survival rate observa-tion

摘要目的:研究系统性淋巴结清扫术治疗子宫内膜癌的有效性及近期生存率。方法选取2013年9月至2014年10月66例子宫内膜癌患者进行回顾性分析,将其随机分为观察组和对照组,每组33例。对照组患者给予全子宫(或次广泛性子宫)切除、附件切除及盆腔淋巴结清扫常规治疗,观察组患者在常规治疗基础上进行系统性腹主动脉旁淋巴结清扫。比较两组患者复发转移率、近期生存率及并发症变化情况。结果观察组患者复发转移率为15.2%,低于对照组(42.2%);观察组患者近期生存率为90.9%,高于对照组(69.7%),差异均有统计学意义(P ﹤0.05)。观察组患者并发症发生率为36.4%,对照组患者术后并发率为36.4%,差异未见统计学意义(P ﹥0.05)。结论系统性淋巴结清扫术应用于子宫内膜癌治疗,能够有效降低患者复发转移率,提高患者生存率。术后并发症虽有升高,但采取相应措施均可得到有效控制。

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abstractsObjective To study the efficacy and recent survival rate of systemic lymphadenecto-my on endometrial cancer. Methods From September 2013 to October 2014,66 cases of endometrial cancer were randomly divided into observation group and control group,with 33 cases in each group. The patients in control group were treated with hysterectomy(or sub radical hysterectomy)removal,oopho-rectomy and pelvic lymphadenectomy conventional treatment,and the observation group received systemic side-aortic lymph node dissection on the basis of conventional treatment. The recurrence rate ,short-term survival rate and complications were compared between the two groups. Results The recurrence rate of observation group was 15. 2% ,which was lower than that in the control group(42. 2% );the recent sur-vival rate of observation group was 90. 9% ,which was higher than that in the control group(69. 7% ), and the differences were significant(P ﹤ 0. 05). The complication rate of observation group was 36. 4% , and 36. 4% in the control group,the difference was not significant(P ﹥ 0. 05). Conclusions System-atic lymphadenectomy in treatment of endometrial cancer can effectively reduce the recurrence rate of pa-tients,improve the survival rate. Although the postoperative complications are increased,but can be ef-fectively controlled by corresponding measures .

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