不同时间窗下延迟经皮冠状动脉介入治疗急性ST段抬高型心肌梗死的临床效果
Clinical value of delayed percutaneous coronary intervention in the treatment of acute ST segment elevation myocardial infarction at different time windows
摘要目的 比较不同发病时期对急性ST段抬高心梗患者进行延迟经皮冠脉介入治疗的价值.方法 抽取晋城市人民医院2015年1月到2017年12月治疗的264例急性ST段抬高心肌梗死患者作为研究对象.按照患者治疗时期不同,将患者分为观察组与对照组.观察组132例,进行时间窗12~24 h的延迟经皮冠状动脉介入治疗.对照组132例,进行时间窗>24 h的介入治疗.治疗后8周,比较两组患者心脏功能、支架置入情况及治疗后1年内心脏不良事件发生率.结果 治疗后,观察组患者与心功能相关指标以及不良事件的发生情况表现优于对照组患者,P<0.05;两组患者支架数目、直径、长度及最大扩张压力等指标比较,差异未见统计学意义(P>0.05).结论 针对急性ST段抬高心梗患者,如果没有及时在发病的12 h内进行再灌注治疗,但只要尽早进行经皮冠状动脉介入同时配合合理的药物干预,则可以获得同等效益.
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abstractsObjective To compare the value of delayed epidermal coronal intervention therapy in patients with acute ST segment elevation of heart attack in different stages of the disease. Methods A total of 264 patients with acute ST segment elevated myocardial infarction treated in Jincheng People's Hospital from January 2015 to December 2017 were selected as research subjects. The patients were divided into observation group and control group according to treatment periods. The 132 patients in the observation group received delayed percutaneous coronary intervention with 12 -24 hours time window, the 132 cases in the control group received interventional therapy with time window > 24 hours. Eight weeks after treatment, cardiac function, stent implantation and incidence of adverse cardiac events in one year after treatment were compared between the two groups. Results After treatment, the patients in the observation group showed better manifastations than those in the control group in cardiac function-related indicators and adverse events (P<0. 05). There was no significant difference in the number, diameter, length and maximum dilatation pressure of stents between the two groups ( P>0. 05 ) . Conclusions For patients with acute ST-segment elevation myocardial infarction, if reperfusion therapy could not be performed within 12 hours of onset in time, performing percutaneous coronary intervention and reasonable drug intervention as early as possible can achieve the same benefits.
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