摘要目的:分析急诊心脏骤停(CA)患者心肺复苏术(CPR)治疗失败的危险因素。方法:抽取2021年1月至2022年1月郑州市第九人民医院急诊科经CPR抢救的CA患者66例，按照抢救结局将其分为成功组(26例)和失败组(40例)。比较两组资料，解析出影响心脏骤停患者CPR术后出现不良结局的危险因素。结果:两组CPR开始时间、自主循环恢复(ROSC)时间、是否为创伤性损伤、肾上腺素使用量比较差异有统计学意义( t＝8.98、12.20，χ 2＝15.64、8.81， P均<0.05)。CPR开始时间、ROSC时间、创伤性损伤、肾上腺素使用量>5 mg是CA患者CPR术后出现治疗失败的危险因素( OR＝6.483、2.998、10.214、4.800， P均<0.05)。 结论:CPR开始时间晚、ROSC时间久、创伤性损伤以及肾上腺素使用量>5 mg是心脏骤停患者经CPR抢救后出现不良结局的危险因素。

abstractsObjective:To analyze the risk factors for failure of cardiopulmonary resuscitation (CPR) in patients with emergency cardiac arrest (CA).Methods:A total of 66 CA patients who were rescued by CPR in Department of Emergency of Zhengzhou Ninth People’s Hospital from January 2021 to January 2022 were selected. According to the rescue outcomes, the patients were divided into success group (26 cases) and failure group (40 cases). The data of the two groups were compared, and the risk factors for adverse outcomes after CPR in patients with cardiac arrest were analyzed.Results:There were significant differences in CPR initation time, return of spontaneous circulation (ROSC), traumatic injury or not, and the dosage of epinephrine between the two groups ( t=8.98, 12.20; χ 2=15.64, 8.81; all P<0.05). CPR initiation time, ROSC time, traumatic injury, and epinephrine dosage > 5 mg were risk factors for treatment failure after CPR in CA patients ( OR=6.483, 2.998, 10.214, 4.800; all P<0.05). Conclusions:Late start of CPR, long ROSC time, traumatic injury and epinephrine dosage >5 mg are risk factors for adverse outcomes in CA patients after CPR.