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无痛胃镜电凝切除术与内镜下电凝切除术治疗增生性胃息肉的对比分析

Comparative analysis of painless endoscopic electrocoagulation gastrectomy and endoscopic electrocoagulation resection in the treatment of gastric hyperplastic polyps

摘要目的:分析无痛胃镜电凝切除术(PEEG)与内镜下电凝切除术(EER)治疗增生性胃息肉(GHP)的效果。方法:队列研究。抽取2023年1月至2023年12月河南省直第三人民医院收治的GHP患者118例,按随机数字表法分为EER组与PEEG组,每组59例。EER组采用EER治疗,PEEG组采用PEEG治疗。比较两组围术期指标、术后恢复情况、炎症指标[肿瘤坏死因子-α(TNF-α)、白细胞介素-6(IL-6)、白细胞介素-8(IL-8)]及并发症发生率。结果:PEEG组手术时间短于EER组,术中出血量少于EER组( P<0.05);PEEG组首次排气、排便、创面愈合及住院时间均短于EER组( P均<0.05);术后7 d,PEEG组TNF-α、IL-6、IL-8水平均低于EER组( P均<0.05)。PEEG组并发症发生率(3.39%,2/59)低于EER组(15.25%,9/59), P<0.05。 结论:与EER相比,PEEG治疗GHP的效果更好,能减少术中出血量,缩短手术用时,减轻术后疼痛,促进患者术后恢复,且并发症较少。

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abstractsObjective:To analyze the effects of painless endoscopic electrocoagulation gastrectomy (PEEG) and endoscopic electrocoagulation resection (EER) in the treatment of gastric hyperplastic polyps (GHP).Methods:A total of 118 patients with GHP admitted to the Third People’s Hospital of Henan Province from January 2023 to December 2023 were selected for the cohort study. According to the random number table, all the subjects were divided into the EER group and the PEEG group, with 59 cases in each group. The EER group was treated by EER, and the PEEG group was treated by PEEG. Perioperative indexes, postoperative recovery, inflammatory indexes, including tumor necrosis factor-α (TNF-α), interleukin-6 (IL-6) and interleukin-8 (IL-8), and incidence of complications were compared between the two groups.Results:The operation duration in the PEEG group was shorter than that in the EER group, and the intraoperative blood loss in the PEEG group was less than that in the EER group ( P<0.05). The time of first exhaust, defecation, wound healing and hospital stay in the PEEG group were shorter than those in the EER group (all P<0.05). The levels of TNF-α, IL-6 and IL-8 in the PEEG group were lower than those in the EER group 7 days after operation (all P<0.05). The incidence of complications in the PEEG group (3.39%, 2/59) was lower than that in the EER group (15.25%, 9/59), P<0.05. Conclusions:Compared with EER, PEEG is more effective in the treatment of GHP, which can reduce intraoperative blood loss, shorten operation duration, alleviate postoperative pain, and promote postoperative recovery of patients, with fewer complications.

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