摘要Implantable cervical vagus nerve stimulation(iVNS)is a representative and promising neuromodulation.However,the invasive nature restricts its application.Traditional auricular acupuncture treatment has a long history.The auricular branch of the vagus nerve(ABVN)is a branch on the surface of the ear.Some studies demonstrates that transcutaneous auricular vagus nerve stimulation(taVNS)would achieve similar effects as iVNS.TaVNS and iVNS share a common anatomical basis and acting mechanism.In this article,we made a comparison between iVNS and taVNS in indications and efficacy.The recent studies have revealed similar clinical efficacy of taVNS,taVNS would expand the indication of iVNS.High-quality clinical evidences are needed before taVNS become be an alternative of iVNS.