VACCINE FOR PREVENTING FELINE CALICIVIRUS INFECTION, AND PREPARATION METHOD THEREFOR AND USE THEREOF
摘要A vaccine for preventing a feline calicivirus disease, and a preparation method therefor and the use thereof. By means of antigen sequence design and screening, an antigen peptide and an mRNA nucleic acid molecule having excellent expression effects are obtained, and thus a vaccine prepared therefrom has a good immune effect and can induce the production of a highly-effective and durable level neutralizing antibody against a feline calicivirus at a very low dose and dosing regimen; meanwhile, the mRNA vaccine has the characteristics of a good stability, a high delivery efficiency, safety, effectiveness and a controllable quality.
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