换一批摘要A multidrug linker, an antibody-drug conjugate comprising the multidrug linker, a preparation method for the antibody-drug conjugate, and uses of the multidrug linker and the antibody-drug conjugate in disease treatment. A specific structure can effectively reduce the aggregation of a multi-payload drug-antibody conjugate, thereby facilitating process scale-up. In addition, payload drugs can achieve a significant synergistic effect, thereby achieving a synergistic anti-tumor effect, effectively overcoming the resistance to drugs, and improving the therapeutic window of drugs.
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申请/专利号
IL32623326A
申请日期
2026-01-28
公开/公告号
公开/公告日
2026-03-01
主分类号
A61K47/54（以所用的非有效成分为特征的医用配制品，例如载体、惰性添加剂）
分类号
A61K47/54 A61P35/00 A61K47/54 A61P35/00
发明/设计人
学术成果认领
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