摘要目的 总结PICU中毒患儿的相关因素,并提出针对性的干预措施.方法 回顾性分析中毒患儿的年龄、发病季节、中毒症状、中毒物质、中毒途径、治疗、转归等,并根据是否为药物中毒分为药物组和非药物组,比较两组不同特点.结果 药物中毒组81例,非药物中毒组54例.两组中毒表现和临床辅助检查差异无统计学意义(P＞0.05).非药物中毒组治愈率和无效率分别为46.30％和1.85％,与药物中毒组相比差异无统计学意义(P＞0.05).但是两组在呼吸机使用时间和血液净化治疗时间方面差异有统计学意义(P＜0.05).从中毒主要因素来看,以家庭中毒为主(82.96％),农村中毒患儿比例较高(59.26％),药物中毒81例(60.00％).结论 针对儿童中毒发生的主要特点,要求家长必须做好相关化工产品的日常管理,掌握正确的药物使用知识,以降低儿童中毒发生风险.

abstractsObjective To summarize the relative factors of PICU poisoning,and then to propose some corresonding intervention measrues.Methods The age,onset season,poisoning symptom,poisoning substance,poisoning way,treatment,prognosis etc.of the poisoning children were retrospectively analyzed.The children were divided into a drug poisoning group and a non-drug poisoning group according to whether was drug poisoning.The different characteristics of the two groups were compared.Results The drug poisoning group had 81 patients,and the non-drug poisoning group 54 cases.There were no statistical differences in the poisoning manifestations and clinical examination between the two groups(P ＞ 0.05).The cure rate and effectless rate of the non-drug poisoning group were 46.30％ and 1.85％,respectively,which didn' t stattistically differ from that of the drug poisoning group (P ＞ 0.05).However,there were statistical differences in the time of applying ventilator and blood purification time between the two groups (P ＜ 0.05).The main poisoning factor was family poisoning (82.96％).Children from countryside had a high poisoning ratio (59.26％).81 cases were drug poisoning (60.00％).Conclusions According to the main characteristics of children poisoning,it propose that the parents manage the relevant chemical products well and have good command of the knowledge of correct drug use to reduce the poisoning risk in children.