摘要慢性阻塞性肺疾病急性加重(AECOPD)是慢性阻塞性肺疾病患者死亡与疾病进展的主要诱因。AECOPD诊治专家组依托近4年来相关文献，第4次更新了共识核心内容，提出AECOPD新的定义、严重程度分级与分级诊疗方案，细化了抗菌药物经验性选择建议，对支气管舒张剂及糖皮质激素的使用、呼吸支持与氧疗策略等方面也进行了更新调整。

abstractsAcute exacerbation of chronic obstructive pulmonary disease (AECOPD) is the main cause of death and disease progression in patients with chronic obstructive pulmonary disease (COPD).Through literature review within the past 4 years, the Expert Group on the Management of Acute Exacerbation of Chronic Obstructive Pulmonary Disease has revised and updated the core contents of the consensus for the fourth time, which has proposed the new definition of AECOPD, and the classification of the severity and corresponding graded diagnosis and treatment regimens.In particular, the empirical selection of antimicrobial agents, and the use of bronchodilators and glucocorticoids have been more specific, and respiratory support and oxygen therapy strategies have been modified as well.