摘要焦虑障碍是发病率最高的精神疾病，过度应激暴露是诱发焦虑障碍等精神疾病的重要因素。大量研究表明，杏仁核内不同环路的神经元结构与功能异常与焦虑的发生密切相关。文章主要综述杏仁核神经环路在焦虑情感表达中的作用，首先阐述杏仁核的结构和环路连接，然后综述在生理状态下与焦虑行为调控有关的杏仁核环路，最后综述在应激诱发焦虑障碍的病理状态下杏仁核环路结构和功能变化及其作用机制，以期为焦虑障碍的防治提供新的理论依据。

abstractsAnxiety disorders are the most prevalent psychiatric disorders. Excessive stress exposure is an essential factor for the development of psychiatric disorders such as anxiety disorders. Numerous studies have shown that the abnormalities of neuronal structure and function in the amygdala are highly correlated with anxiety disorders. This paper mainly focuses on introducing the role of amygdala neural circuits in regulating anxiety behavior. After summarizing the structure and circuit of the amygdala, we discuss recent findings from rodents showing the amygdala circuits that are involved in the regulation of anxiety behavior in physiological state. Finally, we summarize the structural and functional changes of amygdala circuits and the mechanisms in stress-induced anxiety disorders under pathological conditions. We hope this review would provide a new theoretical basis for the prevention and treatment of anxiety disorders.