摘要急性早幼粒细胞白血病(APL)起病凶险，但属于可获得高治愈率的一种疾病，及早和规范诊治是关键。2018年中国儿童APL诊疗规范对规范儿童APL诊治起到了重要作用，然而近年APL的诊断和治疗取得多方面的进展，包括儿童APL，需要更新。为此，中国抗癌协会小儿肿瘤专业委员会采用文献证据级别和专家推荐意见相结合的方法，就我国儿童血液肿瘤专科医师关注的临床问题，制定较为详细的中国18岁以下儿童APL的诊疗指南，旨在提高我国儿童APL诊疗的科学性和治愈率。

abstractsAcute promyelocytic leukemia (APL) is a highly curable disease but very dangerous at onset and develops quickly.Early diagnosis and standardized treatment is critical for curing the disease.In 2018, the Chinese practice guideline on the diagnosis and treatment of childhood APL was first published, constributing greatly to standardized managment of childhood APL in China.Since then, there are significant progresses in the diagnosis and treatment of both adult and childhood APL, thus necessitating an updated edition.Based on the evidence-based medicine and expert recommendations, the Pediatric Oncology Committee, China Anti-Cancer Association develops detailed guidelines for the diagnosis and treatment of APL in children under 18 years focusing primarily issues concerned by pediatrics hematologists and oncologists in China, and aiming at improving the scientificity of managment and prognosis of pediatric APL.