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抑郁症患者认知功能损害及干预研究进展

Research progress on cognitive impairment and intervention in patients with depression

摘要抑郁症是最常见的精神障碍之一,除核心症状外还可伴有认知症状。随着对疾病认识的提高,抑郁症的认知症状越来越被人们所重视,抑郁症患者的认知功能损害不仅在疾病发作期表现出来,在疾病缓解期也可持续存在,对患者的社会功能造成了极大的影响。认知功能评估工具如认知测验、事件相关电位、眼动检查等被运用于抑郁症患者的认知功能评估中,显示抑郁症患者存在多维度的损害。部分治疗方法如运动疗法、经颅磁刺激技术及药物治疗等显示出改善抑郁症患者认知功能的潜力。现对近年来相关领域的研究进行综述,为研究抑郁症患者的认知功能损害及干预提供线索。

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abstractsDepression is one of the most common mental disorders, which can be accompanied by cognitive symptoms in addition to core symptoms.With the improvement of the awareness of the disease, people pay more attention to the cognitive symptoms of depression. The cognitive impairment of patients not only appears in the onset of the disease, but also persists during the remission of the disease, which has a negative impact on the patients’ social function. Some cognitive assessment tools such as cognitive tests, event-related potential(ERP) and eye movement tracking technology have been used to assess cognitive impairment in patients with depression, which show that there are multidimensional cognitive impairments. Some therapeutic methods such as exercise therapy, repetitive transcranial magnetic stimulation(rTMS) and drug therapy have shown the potential to improve the cognitive function of patients with depression. This article reviews related researches in recent years to explore the cognitive impairment and therapeutic methods of patients with depression.

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