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Multi-link Vision and MiniVision stent registry in Asian patients with coronary artery disease: a prospective, multi-center study

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Background Recent studies have showed that the fine mesh stents are associated with a significant reduction in both clinical and angiographic re-stenosis of the coronary arteries. To maintain a very satisfactory radio-opacity using the stents, Guidant of the USA has designed a new type of bare metal stents (BMS)-Multi-link (ML) Vision / ML MiniVision stents. The clinical outcomes of Asian patients with coronary artery disease (CAD) after implanting the Multi-link Vision or MiniVision stent were investigated in this study.Methods An observational, prospective, multi-center, non-randomized post marketing registry was conducted to demonstrate the efficacy of the BMS- ML Vision / ML MiniVision stents. The primary end point of the registry was clinical target lesion revascularization (TLR) at a 6-month follow-up. The major secondary end points included the rate of major adverse cardiac events (MACE) and serious adverse events (SAE) in hospital and at 6 months; and the rate of clinical TLR as a function of the type of angina. A total of 429 Asian people with 449 lesions from 14 centers were selected for this study. The average reference diameter of the lesions was (3.0±0.5) mm, and the mean length was (15.7±5.0) mm.Results The successful rate of the procedure was 99.3%. Twenty-five percent of the lesions were treated by direct stenting without pre-dilation. Eighty-six percent of the lesions were implanted with ML Vision stent. After the 6-month follow-up, the rate of clinical TLR was 1.4%. The MACE, SAE and target vessel revascularization (TVR) were 6.8%, 3.5%and 1.4% respectively.Conclusion The current registry showed the excellent 6-month clinical outcomes of ML Vision/ML MiniVision stents in Asian patients with CAD.

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作者单位: Department of Cardiology, Renmin Hospital of Wuhan University,Wuhan 430063, China [1] Department of Cardiology, Shanghai Tenth People's Hospital, Tongji University, Shanghai 200072, China [2] Department of Cardiology, Chang Hai Hospital, Shanghai 200000,China [3] Department of Cardiology, First Affilated Hospital, Chinese Medical University, Shenyang 110000, China [4] Department of Cardiology, Second Affiliated Hospital, Dalian Medical University, Dalian 116000, China [5] Department of Cardiology, Nanfang Hospital, Guangzhou 510000,China [6] SDMH, Jaipur, India [7] Ruby Hall Clinic, Pune, India [8] Ushamullapudi Cardiac Center, Hyderabad, India [9] Sri Jayadeva Institute of Cardiology, Bangalore, India [10] Phramongkutklao Hospital(Army hospital), Bangkok, Thailand [11] Maharaj Nakom Chiang Mai Hospital, Chiang Mai University,Thailand [12] Samsung Medical Center, Seoul [13] Wonju Christian Hospital - Yonsei University, Seoul [14] University Malaya Medical Center, Kuala Lumpur, Malaysia [15]
期刊: 《中华医学杂志(英文版)》2007年120卷12期 1093-1096页 SCIMEDLINEISTICCSCDBP
分类号: R5
栏目名称: ORIGINAL ARTICLES
发布时间: 2008-03-03
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