摘要为指导基层狂犬病预防控制工作,尤其是暴露后的预防处置及降低死亡,中国CDC组织专家,参考WHO和美国CDC相关技术指南,以及国内外最新研究进展,制定了《狂犬病预防控制技术指南(2016版)》(指南).指南系统回顾了狂犬病的病原学及实验室诊断、临床学、流行病学、疫苗和被动免疫制剂的种类、机制、效果、安全性和不良反应监测与处置,以及暴露预防处置方法等内容的科学证据,在此基础上对狂犬病暴露前和暴露后预防的伤口处置、疫苗接种和被动免疫制剂使用等技术给出推荐建议.指南适用于从事狂犬病防控工作的各级各类疾病预防控制机构、狂犬病暴露预防处置门诊、医疗机构感染科和急诊科等专业人员.本指南也将根据国内外狂犬病研究进展不断更新和完善.

abstractsIn order to promote the prevention and control programs on rabies in our country,to regulate the prevention and disposition of rabies and to reduce the deaths caused by rabies,the Chinese Center for Disease Control and Prevention has organized a panel of experts,in the reference with Guidelines issued by WHO,American Advisory Committee on Immunization Practices,and the latest research progress from home and abroad,and compiled this document—"Technical Guidelines for Human Rabies Prevention and Control (2016)".The Guidelines conducted a systematic review on the etiology,clinical characteristics,laboratory diagnosis,epidemiology of rabies and provided evidence on varieties,mechanisms,effects,side-effects and security of rabies vaccine,as well as on other preparations on passive immunity of its kind,on methods related to prevention and disposition of exposure etc,finally to have come up with the recommendation on the above mentioned various techniques.The guidelines will be used by staff working on prevention and control of rabies from the Center for Disease Control and Prevention at all levels,from the departments of outpatient and divisions of infection and emergency control in all the medical institutions.The guideline will be updated and revised,following the research progress from home and abroad.