摘要氨甲环酸可以通过多个环节治疗黄褐斑,包括抑制真皮血管形成,减少肥大细胞数目并抑制其活性,减少基底膜带损伤,抑制表皮黑素合成和转运,促进皮肤屏障功能恢复等。本文综述氨甲环酸治疗黄褐斑的机制及疗效,为临床应用提供更多依据。
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abstractsTranexamic acid can treat melasma through multiple steps, such as inhibiting dermal angiogenesis, reducing the number of mast cells and inhibiting their activity, reducing damage to the basement membrane zone, inhibiting melanin synthesis and transport in the epidermis, and promoting the recovery of skin barrier function. This review summarizes the action mechanism and efficacy of tranexamic acid in the treatment of melasma, providing more evidence for its clinical application.
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